An evaluation survey on the impact nutrition intervention activities was conducted in Thuong Tin district in April 2004. The survey’s objective was to assess the impact of 10 year-multisectoral intervention activities on household food security and nutritional status of mothers and children. The paper's objective was to introduce the impact of these intervention on nutrition knowledge and practice of mother and nutritional status of children and mothers with children under five years of age. A repeated cross-sectional survey design was applied in 6 communes covered by the nutrition baseline survey in 1995. Weight and height of all mothers with children under five and children under five were taken to assess their nutritional status with WHO recommended method, NCHS reference. The results showed that nutrition knowledge and practice of mothers, nutritional status of both mothers and under five children have been remarkably improved after 10 year multi-sectoral intervention activities were introduced. Strengthening and reinforcing nutrition collaborator net-work, and nutrition information-education and communication through mass media to improve nutrition knowledge of community, especially women in pre-marriage age are fundamental.