Hội chứng chuyển hóa và một số yếu tố liên quan ở người trưởng thành tại thành phố Hồ Chí Minh năm 2020
Mục tiêu: Xác định tỉ lệ hiện mắc hội chứng chuyển hóa (HCCH) và các yếu tố liên quan của hội chứng này ở người trưởng thành 18 – 69 tuổi tại thành phố Hồ Chí Minh.
Phương pháp: Nghiên cứu cắt ngang trên 1424 đối tượng (791 phụ nữ) tuổi trung bình là 44,9 ± 14,7. Các thông tin thu thập gồm tuổi, giới, thói quen hút thuốc, cân nặng, chiều cao,...
Tóm tắt tiếng Việt: Mục tiêu: Xác định tỉ lệ hiện mắc hội chứng chuyển hóa (HCCH) và các yếu tố liên quan của hội chứng này ở người trưởng thành 18 – 69 tuổi tại thành phố Hồ Chí Minh. Phương pháp: Nghiên cứu cắt ngang trên 1424 đối tượng (791 phụ nữ) tuổi trung bình là 44,9 ± 14,7. Các thông tin thu thập gồm tuổi, giới, thói quen hút thuốc, cân nặng, chiều cao, vòng eo, huyết áp và các xét nghiệm máu gồm cholesterol toàn phần, triglyceride, HDL-C, LDL-C, glucose. HCCH được xác định khi có từ 3 trong 5 tiêu chí trở lên: béo bụng, tăng triglycerid, HDL-C thấp, tăng huyết áp, tăng đường huyết lúc đói. Kết quả: Tỉ lệ người trưởng thành mắc HCCH là 36,2% (95% CI: 34,0 – 39,0). Nữ mắc HCCH nhiều hơn nam (39,7% so với 31,9%). Tỉ lệ mắc HCCH có mối liên quan rõ rệt với tuổi và tình trạng thừa cân-béo phì. Ở nhóm 60–69 tuổi tỉ lệ mắc HCCH cao nhất (56,7%) và ở nhóm BMI ≥ 30 kg/m2 tỉ lệ mắc HCCH lên đến 71,7%. Tuy nhiên ở nhóm 18–29 tuổi tỉ lệ mắc HCCH cũng chiếm 10,8%. Trong các thành tố chẩn đoán HCCH, tăng triglycerid máu chiếm tỉ lệ cao nhất là 51,0% tiếp đến là giảm HDL-C 43,4%, tăng huyết áp 42,8%, béo bụng 38,4% và tăng glucose máu chiếm tỉ lệ thấp nhất 24,2%. Kết luận: Tỉ lệ hiện mắc của hội chứng chuyển hóa tại thành phố Hồ Chí Minh đang gia tăng và cần có chiến lược can thiệp dự phòng cho người dân trong thời gian tới. Tài liệu tham khảo 1. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365 (9468):1415-1428. 2. WHO. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 2000; 894:1-253. 3. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15:539-553. 4. Grundy SM. Metabolic syndrome pandemic. Arterioscler Thromb Vasc Biol. 2008;28:629-636. 5. Ranasinghe P, Mathangasinghe Y, Jayawardena R, Hills AP, Misra A. Prevalence and trends of metabolic syndrome among adults in the asia-pacific region: a systematic review. BMC Public Health. 2017; 17(1):101. 6. O'Neill S, O'Driscoll L. Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies. Obes Rev. 2015;16:1-12. 8. Binh TQ, Phuong PT, Nhung BT, Tung D. Metabolic syndrome among a middle-aged population in the Red River Delta region of Vietnam. BMC Endocr Disord. 2014; 14(77). 10. Le NTDS, Kunii D, Hung NT, Sakai T, Yamamoto S. The metabolic syndrome: prevalence and risk factors in the urban population of Ho Chi Minh City. Diabetes Res Clin Pract. 2005; 67 (3):243-250. 13. National Institute of Health. Third report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Chelesterol in Adults (Adult Treatment Panel III). NIH Publication. 2001; 1-3670. 14. Le NTDS, Kusama K, Hung NT, Loan TT, Chuyen NV, Kunii D, et al. Prevalence and risk factors for diabetes in Ho Chi Minh City, Vietnam. Diabet Med. 2004; 21:371-376.
English summary: Aims: To determine the prevalence of metabolic syndrome (MetS) and its associated factors in adults aged 18 - 69 years old in Ho Chi Minh City. Methods: A cross-sectional study with 1424 participants (791 women) with a mean age of 44.9 ± 14.7. Age, gender, smoking habits, weight, height, waist circumference, total cholesterol, triglycerides, HDL-C, LDL-C, glucose, and blood pressure were recorded. MetS was defined by presence of three or more of the following components: abdominal obesity, hypertriglyceridemia, low HDL-cholesterolemia, high blood pressure and high fasting plasma glucose. Results: The prevalence of MetS was 36.2% (95% CI: 34.0–39.0). Momen had more MetS than men (39.7% and 31.9%). The prevalence of MetS had a statistically significant associated with age and overweight and obesity, in the group of 60-69 year old the highest rate of MetS was 56.7% and in the group of BMI ≥ 30 the prevalence of MetS was highest, up to 71.7%. However, in the group of 18-29 years old, the rate of MetS also accounted for 10.8%. Among the diagnostic components of MetS, hypertriglyceridemia accounted for the highest rate of 51.0%, followed by a decrease in HDL-C 43,4%, increased blood pressure 42.8%, abdominal obesity 38.4% and hyperglycaemia accounted for the lowest rate of 24.2%. Conclusion: The prevalence of MetS in Ho Chi Minh City is increasing and there is a need for preventive intervention strategies for this population shortly. References 1. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365 (9468):1415-1428. 2. WHO. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 2000; 894:1-253. 3. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15:539-553. 4. Grundy SM. Metabolic syndrome pandemic. Arterioscler Thromb Vasc Biol. 2008;28:629-636. 5. Ranasinghe P, Mathangasinghe Y, Jayawardena R, Hills AP, Misra A. Prevalence and trends of metabolic syndrome among adults in the asia-pacific region: a systematic review. BMC Public Health. 2017; 17(1):101. 6. O'Neill S, O'Driscoll L. Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies. Obes Rev. 2015;16:1-12. 8. Binh TQ, Phuong PT, Nhung BT, Tung D. Metabolic syndrome among a middle-aged population in the Red River Delta region of Vietnam. BMC Endocr Disord. 2014; 14(77). 10. Le NTDS, Kunii D, Hung NT, Sakai T, Yamamoto S. The metabolic syndrome: prevalence and risk factors in the urban population of Ho Chi Minh City. Diabetes Res Clin Pract. 2005; 67 (3):243-250. 13. National Institute of Health. Third report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Chelesterol in Adults (Adult Treatment Panel III). NIH Publication. 2001; 1-3670. 14. Le NTDS, Kusama K, Hung NT, Loan TT, Chuyen NV, Kunii D, et al. Prevalence and risk factors for diabetes in Ho Chi Minh City, Vietnam. Diabet Med. 2004; 21:371-376.
English summary: Aims: To determine the prevalence of metabolic syndrome (MetS) and its associated factors in adults aged 18 - 69 years old in Ho Chi Minh City. Methods: A cross-sectional study with 1424 participants (791 women) with a mean age of 44.9 ± 14.7. Age, gender, smoking habits, weight, height, waist circumference, total cholesterol, triglycerides, HDL-C, LDL-C, glucose, and blood pressure were recorded. MetS was defined by presence of three or more of the following components: abdominal obesity, hypertriglyceridemia, low HDL-cholesterolemia, high blood pressure and high fasting plasma glucose. Results: The prevalence of MetS was 36.2% (95% CI: 34.0–39.0). Momen had more MetS than men (39.7% and 31.9%). The prevalence of MetS had a statistically significant associated with age and overweight and obesity, in the group of 60-69 year old the highest rate of MetS was 56.7% and in the group of BMI ≥ 30 the prevalence of MetS was highest, up to 71.7%. However, in the group of 18-29 years old, the rate of MetS also accounted for 10.8%. Among the diagnostic components of MetS, hypertriglyceridemia accounted for the highest rate of 51.0%, followed by a decrease in HDL-C 43,4%, increased blood pressure 42.8%, abdominal obesity 38.4% and hyperglycaemia accounted for the lowest rate of 24.2%. Conclusion: The prevalence of MetS in Ho Chi Minh City is increasing and there is a need for preventive intervention strategies for this population shortly. References 1. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365 (9468):1415-1428. 2. WHO. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser. 2000; 894:1-253. 3. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15:539-553. 4. Grundy SM. Metabolic syndrome pandemic. Arterioscler Thromb Vasc Biol. 2008;28:629-636. 5. Ranasinghe P, Mathangasinghe Y, Jayawardena R, Hills AP, Misra A. Prevalence and trends of metabolic syndrome among adults in the asia-pacific region: a systematic review. BMC Public Health. 2017; 17(1):101. 6. O'Neill S, O'Driscoll L. Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies. Obes Rev. 2015;16:1-12. 8. Binh TQ, Phuong PT, Nhung BT, Tung D. Metabolic syndrome among a middle-aged population in the Red River Delta region of Vietnam. BMC Endocr Disord. 2014; 14(77). 10. Le NTDS, Kunii D, Hung NT, Sakai T, Yamamoto S. The metabolic syndrome: prevalence and risk factors in the urban population of Ho Chi Minh City. Diabetes Res Clin Pract. 2005; 67 (3):243-250. 13. National Institute of Health. Third report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Chelesterol in Adults (Adult Treatment Panel III). NIH Publication. 2001; 1-3670. 14. Le NTDS, Kusama K, Hung NT, Loan TT, Chuyen NV, Kunii D, et al. Prevalence and risk factors for diabetes in Ho Chi Minh City, Vietnam. Diabet Med. 2004; 21:371-376.
