English summary: Metabolic
syndrome (MS), also known as the insulin resistant syndrome, consists
of a cluster of metabolic disorders that were strongly associated with
diabetes and cardiovascular diseases. Unbalanced diet (more fat, less
healthy food), sedentary lifestyle which becomes more popular in
developing country including Vietnam were risk factor for the syndrome.
Healthcare-related staff, who provide healthcare to patients were
well-trained in medical field and may had better knowledge on either
general diseases or this syndrome than general population. However,
information about the syndrome in this population in Ho Chi Minh City, a biggest city of Vietnam
is unknown. We sought to determine the prevalence of metabolic syndrome
and its related factors in healthcare-related individuals in Ho Chi Minh City. Five hundreds and four individuals [(125 men, age: 38 ± 10 y) and (379 women, age: 39 ±
10 y) were enrolled in the cross-sectional study. The demographic,
social characteristics and habits were collected using structured
questionnaire. Anthropometric, clinical parameters were measured.
Fasting blood sample was collected for measurement of plasma
concentration and lipid profile. The MS was defined using either
international diabetes foundation (IDF) 2005 criteria which is presence
of central obesity plus presences of two or more of the rest four
components i.e., hyper triglyceride, low HDL-cholesterol, high blood
pressure and, elevated fasting blood glucose or ATP III (for determine
the prevalence only), which is presence of three or more in the five
components above. All statistical analyses were performed using SPSS for
Windows 11.5. A p-value<0.05 was considered significant. Using IDF
criteria, the prevalence of MS is 22% and this prevalence is 13%, based
on ATP III criteria. Women had significantly higher proportion of MS
than men. No relationship between MS and locality. The prevalence of MS
significantly increased with menopause status. However, after adjustment
for age, this relationship is no longer existed. No relationship
between MS and educational level, work type was observed. Compare to
individuals without MS, individuals with MS have significantly higher in
BMI, total body fat, skin-fold thickness, hip circumference and total
cholesterol concentration. After adjustment for age, sex, general linear
model reveals that MS individuals have similar BMI but more total body
fat, skin-fold thickness, hip circumference and total cholesterol
concentration. Binary logistic regression analyses, show that ageing and
sex are associated factors for the prevalence of MS and that total body
fat, hip circumference and total cholesterol concentration were
determinants for the prevalence of MS independently with age, sex and
BMI. In conclusion, the first study of MS in healthcare related staff
shows that the prevalence is 22%, indicating an increasing trend of this
syndrome in Vietnamese population. Our findings also indicate that
ageing, gender (female), total body fat, hip circumference and total
cholesterol concentration are associated determinants for the increased
prevalence of MS. Because of the negative effects of MS on both human
health and society, it suggests that the healthcare staff should pay
attention on their own health and that a national regular screening and
prevention program need to be established.
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